seconal sodium secobarbital Options
seconal sodium secobarbital Options
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Acute or Long-term Agony—Caution ought to be exercised when barbiturates are administered to sufferers with acute or chronic pain, since paradoxical enjoyment may very well be induced or significant symptoms might be masked.
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Caution need to be exercised when Seconal Sodium (secobarbital sodium capsules) is administered into a nursing girl, since small quantities of barbiturates are excreted within the milk.
The following adverse reactions and their incidences had been compiled from surveillance of 1000s of hospitalized clients who been given barbiturates.
Griseofulvin—Phenobarbital seems to interfere with the absorption of orally administered griseofulvin, As a result reducing its blood stage.
Hypnotic doses of barbiturates do not surface to impair uterine action significantly in the course of labor. Total anesthetic doses of barbiturates reduce the force and frequency of uterine contractions. Administration of sedative-hypnotic barbiturates into the mother through labor may bring about respiratory despair during the newborn.
secobarbital will lower the level or effect of artemether/lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Most studies of clinically significant drug interactions occurring with the barbiturates have included phenobarbital. Having said that, the applying of these facts to other barbiturates appears valid and warrants serial blood amount determinations with the appropriate drugs when you will discover a number of therapies.
Barbiturates can result in fetal damage when administered to a pregnant lady. Retrospective, circumstance-controlled research have advised that there might be a connection concerning the maternal consumption of barbiturates in addition to a higher than expected incidence of fetal abnormalities.
secobarbital will lower the level or effect of maraviroc by affecting hepatic/intestinal enzyme CYP3A4 metabolism. what is seconal medication used for Use Warning/Observe.
secobarbital will lower the level or effect of doxorubicin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
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secobarbital will decrease the level or effect of eltrombopag by influencing hepatic enzyme CYP2C9/10 metabolism. Use Caution/Watch.
secobarbital increases effects of ifosfamide by affecting hepatic enzyme CYP2B6 metabolism. Use Warning/Observe. Coadministration of ifosfamide with CYP2B6 inducers may perhaps increase metabolism of ifosfamide to its metabolite. Monitor for increased effects/toxicities if combined with CYP2B6 inducers.